Tuesday, February 21, 2012
ABSORPTION PROCESS
Remember that absorption is the most important step to make sure that drugs administered by mouth reach your blood circulation.
If drugs fail to be absorbed, it indicates that drugs taken might be completely destroyed during transit in the stomach or it might simply means that drug molecules cannot pass through the membrane of the gastrointestinal tract and the blood vessels.
There are few possible reasons for this.
First, it could be that the size of the drug molecule is too big to penetrate through the membrane pores. Secondly, they might be very polar or low lipid solubility.
Failure to be absorbed means expected therapeutic drug concentration cannot be achieved.
Hence, failure to achieve desirable therapeutic effects.
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